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Similar A1C Outcomes in Type 1 Diabetic Patients Undergoing Intensive Diabetes Management With Preprandial Rapid-Acting Insulin and Either CSII or Glargine

  1. Anne Peters Harmel, MD and
  2. Ruchi Mathur, MD
  1. From the Department of Endocrinology, University of Southern California, Los Angeles, California
  1. Address correspondence to Dr. Anne Harmel, Endocrinology, University of Southern California, 2905 Alma Ave., Manhattan Beach, CA 90266. E-mail: momofmax{at}hotmail.com

The importance of achieving and maintaining tight glycemic control in patients with type 1 diabetes is well known (1). Continuous insulin infusion therapy (CSII) has been available for many years, but only recently have reports of efficacy with rapid-acting insulin analogues been published. Similarly, multiple daily injection (MDI) therapy using glargine insulin in conjunction with premeal rapid-acting insulin is relatively new (2).

In our diabetes center, all patients with type 1 diabetes receive …

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