Comparative Roles of Microvascular and Nerve Function in Foot Ulceration In Type 2 Diabetes

Response to Krishnan et al.

  1. Dean T. Williams, MD,
  2. Paul E. Norman, DS and
  3. Michael C. Stacey, DS
  1. From the Fremantle Hospital, School of Surgery and Pathology, Fremantle, Western Australia, Australia
  1. Address correspondence to Dean T. Williams, University of Wales College of Medicine, Wound Healing Research Unit, Heath Park, Cardiff, Wales CF14 4UJ, U.K. E-mail: dwill1964{at}aol.com

We have read the article by Krishnan et al. (1) with much interest. The article found that there was a difference between foot microcirculation in subjects with and without diabetes, but there was no difference between patients with diabetes with or without foot ulceration. There are points in the methodology and conclusions regarding the microcirculatory investigations that we would like to raise with the authors and would be grateful for their opinion. In the methodology, their …

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