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Diabetes, Depression, and Quality of Life

A population study

  1. Robert D. Goldney, MD,
  2. Pat J. Phillips, MA,
  3. Laura J. Fisher, BA HONS and
  4. David H. Wilson, PHD
  1. Department of Psychiatry, University of Adelaide, The Adelaide Clinic, Park Terrace, Gilberton, South Australia
  1. Address correspondence and reprint requests to Professor Robert Goldney, Department of Psychiatry, University of Adelaide, The Adelaide Clinic, Park Terrace, Gilberton, South Australia 5081. E-mail: robert.goldney{at}adelaide.edu.au

Abstract

OBJECTIVE—The aim of the study was to assess the prevalence of diabetes and depression and their associations with quality of life using a representative population sample.

RESEARCH DESIGN AND METHODS—The study consisted of a representative population sample of individuals aged ≥15 years living in South Australia comprising 3,010 personal interviews conducted by trained health interviewers. The prevalence of depression in those suffering doctor-diagnosed diabetes and comparative effects of diabetic status and depression on quality-of-life dimensions were measured.

RESULTS—The prevalence of depression in the diabetic population was 24% compared with 17% in the nondiabetic population. Those with diabetes and depression experienced an impact with a large effect size on every dimension of the Short Form Health-Related Quality-of-Life Questionnaire (SF-36) as compared with those who suffered diabetes and who were not depressed. A supplementary analysis comparing both depressed diabetic and depressed nondiabetic groups showed there were statistically significant differences in the quality-of-life effects between the two depressed populations in the physical and mental component summaries of the SF-36.

CONCLUSIONS—Depression for those with diabetes is an important comorbidity that requires careful management because of its severe impact on quality of life.

Footnotes

  • R.D.G. has been on an advisory panel for Sanofi Synthelabo; has received honoraria from Sanofi Synthelabo, Pfizer Australia, and Organon; and has received grant support from Wyeth Australia and Pfizer Australia. P.J.P. has been on advisory panels for AstraZeneca, Aventis, GlaxoSmithKline, and Parke Davis; has received honoraria from Abbott, Eli Lilly, Novartis, and Roche; and has received grant support from Bristol Meyer Squibb, Merck Sharp & Dohme, Novo Nordisk, Pfizer, Sanofi-Synthelabo, and Takeda. D.H.W. has received honoraria from Wyeth Australia and Pfizer Australia for the analysis of the data in this study.

    A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

    • Accepted January 22, 2004.
    • Received July 14, 2003.
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