Seasonal Changes in Body Composition and Blood HbA1c Levels Without Weight Change in Male Patients With Type 2 Diabetes Treated With Insulin

  1. Motoi Sohmiya, MD, PHD,
  2. Ippei Kanazawa, MD and
  3. Yuzuru Kato, MD, PHD
  1. From the Department of Endocrinology, Metabolism and Hematological Oncology, Shimane University School of Medicine, Izumo, Japan
  1. Address correspondence to Motoi Sohmiya MD, PhD, Department of Endocrinology, Metabolism and Hematological Oncology, Shimane University School of Medicine, Izumo 693-8501, Japan. E-mail: motoi{at}med.shimane-u.ac.jp

We have often observed increases in plasma glucose and HbA1c levels in patients with type 2 diabetes during the winter in Japan. This phenomenon has been explained in part by weight gain due to increases in food intake and decreases in exercise during the winter. However, HbA1c levels are also increased during the winter season in most patients with type 2 diabetes without weight gain. In this study, we examined the relationship between seasonal changes in body composition and blood HbA1c levels in patients with type 2 diabetes treated with insulin over a 2-year period.

Eleven male patients with type 2 diabetes treated with insulin were investigated. …

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