Negative Pressure Suction During Blood Sampling May Reduce the Difference in Self-Monitoring of Blood Glucose Results Between Fingertip Pricking and Forearm Pricking
- Keiko Arimoto, MD,
- Hideyuki Sasaki, MD, PHD,
- Kenichi Ogawa, MD,
- Hiroshi Yamasaki, MD,
- Kunihisa Okamoto, MD, PHD,
- Hiroto Furuta, MD, PHD,
- Tadashi Hanabusa, MD, PHD,
- Masahiro Nishi, MD, PHD,
- Taisei Nakao, MD, PHD and
- Kishio Nanjo, MD, PHD
- From the First Department of Medicine, Wakayama Medical University, Wakayama, Japan
- Address correspondence and reprint requests to Hideyuki Sasaki, MD, PhD, First Department of Medicine, Wakayama Medical University, Kimiidera 811-1, Wakayama, Japan. E-mail: sasaki-h{at}wakayama-med.ac.jp
- ITT, insulin tolerance test
- OGTT, oral glucose tolerance test
- SMBG, self-monitoring of blood glucose
Self-monitoring of blood glucose (SMBG) at alternate puncture sites, such as the forearm, gives users an alternative to fingertip puncture, which can be painful. However, it has been reported that blood glucose values obtained at alternate sites are different from those obtained at the fingertip. We aimed to examine whether SMBG results obtained at the forearm are clinically identical to those at the fingertip and whether blood sampling technique by negative pressure suction could reduce the fingertip-to-forearm differences.
RESEARCH DESIGN AND METHODS
Five male volunteers were recruited. A 75-g oral glucose tolerance test (OGTT) identified four individuals with impaired glucose tolerance and one with diabetes. Subject age, HbA1c, fasting venous plasma glucose, and BMI were 50.4 ± 2.1 years, 5.2 ± 0.3%, 95 ± 10 mg/dl, and 23.1 ± 0.6 kg/m2, respectively (means ± SE). Each participant was fully informed about the experiment and signed the consent form before the study began.
OGTT and insulin tolerance test (ITT) were continuously performed in the fasting state. OGTT was performed using the usual methods; blood glucose levels were monitored at 0, 30, 60, 90, and 120 min after the ingestion of a 75-g glucose solution. After the blood collection at 120 min of the OGTT, ITT was started by intravenous administration of insulin at 0.1 unit/1 kg body wt. The …
