The Prospective Pioglitazone Clinical Trial in Macrovascular Events (PROactive)
Table 1—
Baseline characteristics of the PROactive study population and other clinical history (dependent on medical opinion of investigator)
| n | 5,238 |
| Demographic data | |
| Age (years) | 61.8 ± 7.7 |
| Male | 3,463 (66.1) |
| Caucasian | 5,162 (98.5) |
| Duration of type 2 diabetes (years) | 9.5 ± 7.0 |
| Physical examination measurements | |
| Weight (kg) | 88.0 ± 15.6 |
| BMI (kg/m2) | 30.9 ± 4.8 |
| Waist circumference (cm) | 105.3 ± 11.9 |
| Systolic blood pressure (mmHg) | 143.4 ± 17.8 |
| Diastolic blood pressure (mmHg) | 83.0 ± 9.7 |
| Laboratory data | |
| Triglycerides (mmol/l) | 2.24 ± 1.81 |
| HDL cholesterol (mmol/l) | 1.16 ± 0.31 |
| LDL cholesterol (mmol/l) | 2.96 ± 0.95 |
| Creatinine (μmol/l) | 82.55 ± 23.2 |
| HbA1c (%) | 8.08 ± 1.41 |
| Other clinical history | |
| Angina | 3,010 (57.5) |
| Claudication | 1,239 (23.7) |
| Amputation | 72 (1.4) |
| Transient ischemic attack | 299 (5.7) |
| Retinopathy | 1,214 (23.2) |
| Photocoagulation therapy* | 345 (28.4) |
| Nephropathy | 41 (14.2) |
| Neuropathy | 1,340 (25.6) |
| Hypertension | 3,952 (75.4) |
| Current/past smoking | 722 (13.8)/2,358 (45.0) |
-
Data are means ± SD and n (%).
- *
↵* Expressed as a percentage of patients with retinopathy.
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