Multiple Symmetric Lipomatosis: A Paradigm of Metabolically Innocent Obesity?
Response to Haap et al.
- Igor A. Harsch, MD1,
- Simin Pour Schahin, MD1 and
- Roderich Wiedmann, MD2
- 1Department of Medicine I, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany
- 2Department of Surgery, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany
- Address correspondence to Igor Alexander Harsch, MD, Department of Medicine I, Friedrich-Alexander University, Division of Endocrinology and Metabolism, Ulmenweg 18, 91054 Erlangen, Germany. E-mail: igor.harsch{at}med1.imed.uni-erlangen.de
The study of Haap et al. (1) on two patients with multiple symmetric lipomatosis (MSL), also known as the Launois-Bensaude Syndrome, adds interesting new insights into a condition still poorly understood.
As for the conclusions drawn concerning insulin sensitivity in patient 1, we would like to suggest some caution. Our study group has also measured the insulin sensitivity index (ISI) in three subjects with MSL with the euglycemic-hyperinsulinemic …
