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Poor Correlation of Pulse-Wave Velocity and Intima-Media Thickness in Diabetic Subjects

  1. Yuichi Nishi, MD12,
  2. Hiroyuki Koshiyama, MD, PHD12,
  3. Sachiko Honjo, MD1 and
  4. Yutaka Seino, MD, PHD23
  1. 1Center for Diabetes and Endocrinology, Tazuke Kofukai Foundation Medical Research Institute, Kitano Hospital, Osaka, Japan
  2. 2Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
  3. 3Center for Diabetes and Nutrition, Kansai Denryoku Hospital, Osaka, Japan
  1. Address correspondence to Dr. Hiroyuki Koshiyama, MD, Kitano Hospital, Tazuke Kofukai Foundation Medical Research Institute, Center for Diabetes and Endocrinology, Osaka 530-8480, Japan. E-mail: h-koshiyama{at}kitano-hp.or.jp

Various noninvasive in vivo assessments have recently been applied to the estimation of atherosclerosis in subjects with diabetes. The measurement of pulse-wave velocity (PWV) has been popular with the advance of apparatus, especially in Japan (1–3). However, it remains unknown whether PWV may be valid and reproducible, especially in diabetic study populations (4). In a recent issue of Diabetes Care, Hope et al. (5) addressed the important question of whether it is valid to apply PWV in diabetic subjects. They found that the generalized …

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