Hypoglycemic Coma in a Diabetic Patient on Peritoneal Dialysis due to Interference of Icodextrin Metabolites With Capillary Blood Glucose Measurements
- Emmanuel Disse, MD and
- Charles Thivolet, MD, PHD
- From the Department of Endocrinology and Diabetes, Hopital Edouard Herriot, Lyon, France
- Address correspondence to Pr. Charles Thivolet, Department of Endocrinology and Diabetes, Hopital Edouard Herriot, Place d’Arsonval, 69003 Lyon, France. E-mail: charles.thivolet{at}chu-lyon.fr
Continuous ambulatory peritoneal dialysis is used in about one-third of the diabetic population as an alternative to hemodialysis for end-stage renal disease (ESRD). Several case reports and articles (1–3) have alerted health professionals on the potential interference of dialysis fluid containing 7.5% icodextrin, a cornstarch-derived glucose polymer (Extraneal; Baxter Healthcare, Castlebar, Ireland), with some glucose reagent systems using a glucose dehydrogenase enzyme …











