Hypoglycemia Following a Nateglinide Overdose in a Suicide Attempt
- Shiho Nakayama, MD,
- Takahisa Hirose, MD,
- Hirotaka Watada, MD,
- Yasushi Tanaka, MD and
- Ryuzo Kawamori, MD
- From the Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
- Address correspondence to Dr. Takahisa Hirose, Department of Medicine, Juntendo University School of Medicine, 2-1-1 Hongo, Tokyo 113-8421, Japan. E-mail: hirosemd{at}med.juntendo.ac.jp
Various drugs are currently used for the treatment of diabetes. Several reports on overdose of these drugs, especially on sulfonylurea and metformin, have been published (1,2); however, few such publications are available on nateglinide, a rapid insulin secreatagogue. We report the first case of attempted suicide by nateglinide overdose. A 30-year-old Japanese nondiabetic woman was transferred to the emergency department of our hospital 1 h after (6:30 a.m.) ingesting 3,420 mg (38 tablets, 90 mg each) of nateglinide, which was prescribed to her diabetic partner. She had a mild psychiatric history and used minor tranquilizers occasionally. Upon arrival to the hospital, she was able to …
