Effect of High-Dose Vitamin E on Insulin Resistance and Associated Parameters in Overweight Subjects
Response to Manning et al.
- Salvador Vale, MD
- From Indesalud, Campeche, México
- Address correspondence to Salvador Vale, Indesalud, Campeche, México, Calle 14 por 49, 24010 Campeche, México. E-mail: svalemayorga{at}yahoo.com.mx
In the report of Manning et al. (1), patient’s plasma peroxides were decreased by 29% at 6 months with a transient reduction in insulin resistance. Consequently, they postulate that vitamin E improves oxidative stress and hepatocellular function in overweight patients and suggest that “vitamin E could have a role to play in delaying the onset of diabetes in at-risk individuals (1).”
The rationale for …
