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Detection of Silent Myocardial Ischemia in Asymptomatic Diabetic Subjects

Response to Wackers et al.

  1. Narendra C. Bhalodkar, MD and
  2. Steve Blum, PHD
  1. From the Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, New York
  1. Address correspondence to Narendra C. Bhalodkar, MD, FACC, FACP, Division of Cardiology, 12th Floor, Bronx Lebanon Hospital Center, 1650 Grand Concourse, Bronx, NY 10457. E-mail: nbhalodkar{at}yahoo.com

We read the results of the DIAD study (1) with great interest and congratulate all of the investigators. However, the study leaves some questions unanswered and raises others.

1) Since there is no nondiabetic control group with similar baseline characteristics, we don’t know whether the reported prevalence of silent ischemia (22%) is higher than in nondiabetic patients. Such a comparison is necessary to determine how many scans are needed to diagnose one addional silent ischemia in asymptomatic diabetic patients. Therefore, the clinician is not assisted in determining whether performing …

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