Serum Vitamin C Levels in Type 2 Diabetic Nephropathy
- Kenzo Iino, MD12,
- Takuko Fukui, MD1,
- Keizo Anzai, MD1,
- Masanori Iwase, MD2,
- Kazuhiko Kogawa, MD1,
- Masaro Ogimoto, MD1,
- Junko Ono, MD1,
- Takashi Asano, MD1,
- Mitsuo Iida, MD2 and
- Kazuo Tamura, MD1
- 1The First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka, Japan
- 2Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
- Address correspondence to Kenzo Iino, MD, Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Maidashi 3-1-1, Higashi-ku, Fukuoka City, 812-8582, Japan. E-mail: iinok{at}mist.ocn.ne.jp
Serum vitamin C concentrations have been reported to be low in diabetic patients (1). Diabetic nephropathy is known to develop in diabetic individuals, and decreased renal function and hypertension could reportedly accelerate atherosclerosis in patients with type 2 diabetes (2). Observational epidemiologic studies showed an inverse relation between the dietary intake or serum levels of vitamin C and blood pressure (3). Although reduced concentrations of vitamin C were reported …
