B-Type Natriuretic Peptide in Type 2 Diabetes
The influence of chronic renal failure and food
- Liu Chung, MD1,
- Agnès Georges, PHARMD2,
- Jean Benoit Corcuff, MD, PHD2,
- Laurence Bordenave, MD, PHD2,
- Henri Gin, MD, PHD1 and
- Vincent Rigalleau, MD, PHD1
- 1Nutrition-Diabétologie, Hopital Haut-Lévêque and Université Victor Segalen-Bordeaux 2, Pessac, France
- 2Médecine Nucléaire, Hopital Haut-Lévêque and Université Victor Segalen-Bordeaux 2, Pessac, France
- Address correspondence to Vincent Rigalleau, Nutrition-Diabétologie, Hopital Haut-Lévêque, Avenue de Magellan, 33600 Pessac, France. E-mail: vincent.rigalleau{at}wanadoo.fr
Cardiac ventricles release B-type natriuretic peptide (BNP) in response to volume expansion and pressure overload; therefore, BNP concentration may be used as a biochemical marker of cardiac failure (1). BNP levels are high in diabetic subjects with left ventricular dysfunction (2). Because the diagnosis of cardiac failure may be an emergency (3), it is important to know whether the timing of BNP measurement (before or after a meal) affects the result. The effect of renal failure is also an important practical issue, since 25–40% of diabetic subjects have diabetic nephropathy. This study was designed to …
