Is Atherosclerosis in Diabetes and Impaired Fasting Glucose Driven by Elevated LDL Cholesterol or by Decreased HDL Cholesterol?
Response to Schulze and Hoffmann
- Heinz Drexel, MD12,
- Stefan Aczel, MD12,
- Thomas Marte, MD1,
- Werner Benzer, MD2,
- Peter Langer, PHD1,
- Willi Moll, MD3 and
- Christoph H. Saely, MD12
- 1Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria
- 2Department of Medicine, Academic Teaching Hospital Feldkirch, Feldkirch, Austria
- 3Institute for Clinical Chemistry, Feldkirch, Austria
- Address correspondence to Heinz Drexel, MD, Professor of Medicine, VIVIT, Carinagasse 47, A-6800 Feldkirch, Austria. E-mail: vivit{at}lkhf.at
Our study (1) demonstrates that an LDL-related lipid factor in coronary patients with type 2 diabetes is 1) not elevated, 2) not associated with significant coronary stenoses, and 3) not significantly predictive for future events. Whereas the first two findings did not even show a trend for the LDL-related factor, our prospective data need to be confirmed by a longer follow-up with more end points. We have …
