Depressive Symptoms, Insulin Resistance, and Risk of Diabetes in Women at Midlife
Response to Everson-Rose et al.
- Frans Pouwer, PHD1 and
- Peter de Jonge, PHD23
- 1Diabetes Research Group, EMGO Institute, VU University Medical Center (FP), Amsterdam, the Netherlands
- 2Department of Internal Medicine, University Groningen (PdJ), Groningen, the Netherlands
- 3Department of Psychiatry, University Groningen (PdJ), Groningen, the Netherlands
- Address correspondence to Dr. F. Pouwer, Diabetes Research Group, EMGO Institute, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, Netherlands. E-mail: f.pouwer{at}vumc.nl
We read with interest the article by Everson-Rose et al. (1), which indicated that depressive symptoms were associated with a greater risk of diabetes at 3-year follow-up. The authors discussed several mechanisms by which depression may contribute to subsequent insulin resistance and type 2 diabetes, in particular, excess cortisol and central adiposity, altered immune function, and …
