Glycemic Index, Glycemic Load, and Glycemic Response Are Not the Same

  1. Alan W. Barclay, BSC, GRADDIPDIET1,
  2. Jennie C. Brand-Miller, PHD1 and
  3. Thomas M.S. Wolever, MD, PHD2
  1. 1School of Molecular and Microbial Biosciences, University of Sydney, Sydney, Australia
  2. 2Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
  1. Address correspondence to Alan Barclay, Diabetes Australia, GPO Box 9824, Sydney, NSW, 2001, Australia. E-mail: awbarclay{at}optusnet.com.au

The paper by Hodge et al. (1) published in the November 2004 issue of Diabetes Care aptly contrasts the potential benefits of moderately high-carbohydrate diets with a low glycemic index (GI) versus diets that have a lower glycemic load (GL) by virtue of a low carbohydrate content. In their prospective analysis of a cohort of ∼36,000 adults followed for 4 years, Hodge et. al found that higher-carbohydrate diets were associated with a lower risk of development of type 2 diabetes. However, the type of carbohydrate was equally important: low-GI carbohydrates reduced the risk, while high-GI carbohydrates increased the risk. Thus, low GI and low GL are not equivalent and produce …

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