Advertisement

The Burden and Treatment of Diabetes in Elderly Individuals in the U.S.

  1. Elizabeth Selvin, PHD, MPH12,
  2. Josef Coresh, MD, PHD123 and
  3. Frederick L. Brancati, MD, MHS123
  1. 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
  2. 2Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland
  3. 3Johns Hopkins School of Medicine, Baltimore, Maryland
  1. Address correspondence and reprint requests to Elizabeth Selvin, PhD, MPH, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, 2024 E. Monument St., Suite 2-600, Baltimore, MD 21287. E-mail: lselvin{at}jhsph.edu

Abstract

OBJECTIVE—To assess the prevalence of diabetes, distinguishing between elderly individuals with diabetes diagnosed in middle age (“middle age–onset diabetes”) from elderly individuals with recently diagnosed diabetes (“elderly onset diabetes”) and to assess the burden of complications and control of cardiovascular risk factors in these groups.

RESEARCH DESIGN AND METHODS—We analyzed data from 2,809 elderly individuals from the 1999–2002 National Health and Nutrition Examination Survey, a cross-sectional nationally representative survey of the civilian noninstitutionalized population of the U.S.

RESULTS—Among adults aged ≥65 years, the prevalence of diagnosed diabetes was 15.3%, representing 5.4 million individuals in the U.S. The prevalence of undiagnosed diabetes was 6.9% or 2.4 million individuals. Elderly individuals with middle age–onset diabetes had a much greater burden of microvascular disease but have a similar burden of macrovascular disease compared with individuals with elderly onset diabetes. Elderly individuals with middle age–onset diabetes had substantially worse glycemic control (proportion of individuals with HbA1c >7% = 59.9%) compared with either elderly onset (41.6%) or nonelderly individuals with diabetes (55.3%). Individuals with elderly onset diabetes were also less likely to be taking glucose-lowering medications.

CONCLUSIONS—In this study, we documented a high prevalence of diabetes among elderly individuals and high rate of poor glycemic control in this population. Individuals with middle age–and elderly onset diabetes appear to represent distinct groups with differing burdens of disease and possibly differing treatment goals. Future studies of diabetes in elderly individuals may need to consider stratification based on age of diagnosis.

Footnotes

  • A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

    The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.

    • Accepted August 4, 2006.
    • Received May 23, 2006.
| Table of Contents
Advertisement