On the Weighted-Average Relationship Between Plasma Glucose and HbA1c
- Oliver J. Gibson, MENG,
- Patrick E. McSharry, DPHIL and
- Lionel Tarassenko, DPHIL
- From the Department of Engineering Science, University of Oxford, Oxford, U.K
- Address correspondence to Oliver J. Gibson, Department of Engineering Science, University of Oxford, Parks Road, Oxford, OX1 3PJ, U.K. E-mail: oliver{at}robots.ox.ac.uk
HbA1c (A1C) is widely used to assess glycemic control in clinical and research settings, but the precise relationship between A1C and preceding self-monitored plasma glucose measurements is recognized to be complex. It has been reported that measuring plasma glucose levels in the 120 days before an A1C measurement has a nonuniform effect on the result depending on the time that has elapsed between the glucose level and subsequent A1C measurement (1). Tahara and Shima (2) attempted to model this weighted-average …
