Is Pregnancy Outcome Worse in Type 2 Than in Type 1 Diabetic Women?

  1. Natalia Hillman, MD,
  2. Lucrecia Herranz, MD, PHD,
  3. Pilar M. Vaquero, MD,
  4. Africa Villarroel, MD,
  5. Alberto Fernandez, BM and
  6. Luis F. Pallardo, MD, PHD
  1. From the Division of Diabetes, Department of Endocrinology and Nutrition, University Hospital La Paz, Madrid, Spain
  1. Address correspondence to Natalia Hillman Gadea, Division of Diabetes, Department of Endocrinology and Nutrition, University Hospital La Paz, 28046 Madrid, Spain. E-mail: nhillman.hulp{at}salud.madrid.org

Most research on pregestational diabetes has focused on type 1 diabetes, and surprisingly little knowledge exists concerning outcomes of pregnancies of women with type 2 diabetes. A dearth of published data suggest outcomes similar to those of type 1 diabetic women (1,2), although recent studies report poorer outcomes in women with type 2 diabetes (3–7).

We retrospectively compared maternal and perinatal outcomes of 93 consecutive singleton pregnancies in women with type 2 diabetes and 532 consecutive singleton pregnancies in women with type 1 diabetes referred to the Diabetes and Pregnancy Unit at University Hospital La Paz from 1984 to 2004.

Women with type 2 diabetes were significantly older ([means ± SD] 31.8 ± 5.5 …

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