Effect of Multifactorial Intervention on Diabetic Macular Edema
- Ramandeep Singh, MD1,
- Vidya Abhiramamurthy, MBBS1,
- Vishali Gupta, MD1,
- Amod Gupta, MD1 and
- Anil Bhansali, MD2
- 1Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
- 2Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
- Address correspondence to Amod Gupta, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. E-mail: eyepgi{at}sify.com
Clinical trials (1, 2) have shown that intensive control of blood glucose and hypertension reduce development of clinically significant macular edema (CSME). Elevated HbA1c (A1C) is a risk for persistent CSME (3). Gross proteinuria is associated with a 95% increase in the incidence of macular edema (4). However, the effect of control of systemic factors before focal laser photocoagulation is not known. We aimed to determine whether multifactorial intervention over 4–6 weeks before focal laser photocoagulation would reduce …
