On the Weighted-Average Relationship Between Plasma Glucose and HbA1c
Response to Treviño
- Yasuhiro Tahara, MD, PHD1
- Division of Internal Medicine, Meimai Central Hospital, Matsugaoka, Akashi, Japan
- Address correspondence to Yasuhiro Tahara, Division of Internal Medicine, Meimai Central Hospital, Matsugaoka 4-1-32, Akashi, Hyogo 673-0862, Japan. E-mail: ystahara{at}zeus.eonet.ne.jp
Dr. Treviño (1) has derived a mathematical formula for HbA1c (A1C) change in response to exponential plasma glucose decay. His analysis has shown a faster decay of A1C associated with a slower decay of plasma glucose and posed a question to the weighted-average relationship between plasma glucose and A1C, which we proposed in our previous study (2). Since his derived formula is very complicated and the detailed analytical method is not given, I cannot exactly reply to his question. However, I propose here a new physiological model, which deals with the …
