A Case of Fulminant Type 1 Diabetes Associated With Painless Thyroiditis
- Akihiro Hamasaki, MD1,
- Takao Taniguchi, MD, PHD1,
- Shunsuke Yamane, MD1,
- Midori Ida, MD1,
- Motozumi Okamoto, MD, PHD1,
- Yuichiro Yamada, MD, PHD2,
- Nobuya Inagaki, MD, PHD2 and
- Yutaka Seino, MD, PHD23
- 1Department of Internal Medicine, Otsu Red Cross Hospital, Otsu, Shiga, Japan
- 2Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
- 3Kansai-Denryoku Hospital, Osaka, Japan
- Address correspondence to Akihiro Hamasaki, Department of Internal Medicine, Otsu Red Cross Hospital, 1-1-35, Nagara, Otsu, Shiga 520-8511 Japan. E-mail: hamasaki{at}metab.kuhp.kyoto-u.ac.jp
Type 1 diabetes is classified as type 1A and type 1B diabetes, which are considered to be caused by autoimmune and nonautoimmune (idiopathic) mechanisms, respectively (1). Fulminant type 1 diabetes is characterized by a rapid-onset diabetic ketoacidosis within a short period of time, normal to near-normal HbA1c level at onset, and complete β-cell destruction and was originally reported as a subtype of type 1B diabetes (2). Recently, the involvement of viral infections has been suggested to be the triggering mechanism of fulminant type 1 diabetes (3,4). The involvement of T-cell autoimmunity in this disease, however, has also been reported (5–8). Thus, its etiology is still unclear. Here, we report a case of fulminant type 1 …
