Severe Injection Site Reaction to Insulin Detemir

  1. Ian R. Blumer, MD, FRCP
  1. From the Charles H. Best Diabetes Centre, Ajax, Ontario, Canada
  1. Address correspondence to Dr. Ian R. Blumer, 401-95 Bayly St. West, Ajax, ON, Canada. E-mail: ian{at}ianblumer.com

Insulin detemir is a new long-acting insulin analog. Though generally well tolerated, injection site reactions have been reported in 2% of insulin detemir users (1). Most commonly, these untoward reactions manifest as mild injection site erythema or discomfort and seldom lead to discontinuation of the product. Herein, I report the case of a patient with a severe local reaction to insulin detemir necessitating its withdrawl.

A 37-year-old Caucasian woman with a 25-year history of type 1 diabetes was switched from NPH (Humulin …

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