Maternal Weight Gain Is Associated With Infant Insulin Concentrations During the 1st Year of Life
- Donna M. Winham, DRPH1,
- Carol S. Johnston, PHD1 and
- Kristen M. Rhoda, MS1
- Department of Nutrition, Arizona State University, Mesa, Arizona
- Address correspondence to Carol S. Johnston, PhD, Department of Nutrition, Arizona State University, 7001 East Williams Field Rd., Mesa, AZ 85212. E-mail: carol.johnston{at}asu.edu
Since hyperinsulinemia tracks from childhood to adulthood and is associated with diabetes risk, identifying modifiable conditions during gestation that may impact insulin metabolism in offspring is important. We conducted a pilot study to investigate associations between maternal weight gain and infant insulin concentrations in an underserved population at high risk for diabetes. Mexican or Native American women with an infant <1 year of age provided written consent. Infant weight-for-age Z scores (WAZ) were calculated, and nonfasting plasma samples were analyzed for insulin by standard assay. Pearson’s bivariate test was used to assess relationships between variables, and …
