The Metabolic Syndrome and Glucose Tolerance Status Deterioration Over 23-Year Follow-Up
- Rachel S. Dankner, MD, MPH12,
- Angela Chetrit, MA1 and
- Uri Goldbourt, PHD23
- 1Cardiovascular Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel-Hashomer, Israel
- 2Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
- 3Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Hashomer, Israel
- Address correspondence to Rachel Dankner, MD, MPH, Cardiovascular Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel-Hashomer, 52621. Israel. E-mail: racheld{at}gertner.health.gov.il
Individuals with impaired glucose tolerance or impaired fasting glucose are at high risk of developing type 2 diabetes and cardiovascular diseases (1). Identifying those individuals whose glucose tolerance status (GTS) will deteriorate over the years would be of public health importance, due to its preventive implications.
We assessed the metabolic syndrome and lifestyle habits as predictors of 23-year GTS deterioration among survivors of a nationwide longitudinal study (the Israeli Glucose Intolerance, Obesity and Hypertension Study) subsample (2). The study was approved by the institutional review board, and all subjects gave written informed consent. Among the …
