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A Single Factor Underlies the Metabolic Syndrome: A Confirmatory Factor Analysis

Response to McCaffery et al.

  1. Manel Pladevall, MD, MS123,
  2. Bonita Singal, MD, PHD4,
  3. L. Keoki Williams, MD, MPH1,
  4. Carlos Brotons, MD, PHD5,
  5. Heidi Guyer, MPH26,
  6. Josep Sadurni, MD2,
  7. Carles Falces, MD2,
  8. Manuel Serrano-Rios, MD, PHD7,
  9. Rafael Gabriel, MD, PHD8,
  10. Jonathan E. Shaw, MD, FRACP9,
  11. Paul Z. Zimmet, MD, PHD9 and
  12. Steven Haffner, MD, MPH10
  1. 1Center for Health Services Research, Henry Ford Health System, Detroit, Michigan
  2. 2Cardiology Department, Hospital General de Vic, Barcelona, Spain
  3. 3Programa de Doctorat del Departament de Medicina Interna, Universitat Autònoma de Barcelona, Barcelona, Spain
  4. 4Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan
  5. 5Equip d’atenció Primària Sardenya, Barcelona, Spain
  6. 6Institute for Social Research, University of Michigan, Ann Arbor, Michigan
  7. 7Internal Medicine Department, Hospital Clínico San Carlos, Madrid, Spain
  8. 8Clinical Epidemiology Department, Hospital Universitario La Paz, Madrid, Spain
  9. 9International Diabetes Institute, Caulfield, Victoria, Australia
  10. 10University of Texas Health Science Center, San Antonio, Texas
  1. Address correspondence to Manel Pladevall, Center for Health Services Research, Henry Ford Health System, One Ford Pl., 3A, Detroit, MI 48202. E-mail: mpladev1{at}hfhs.org

We thank McCaffery et al. (1) for their comments on our study (2). In their first report (3), they used confirmatory factor analysis to analyze the metabolic syndrome structure and to expose the limitations of exploratory factor analysis (EFA). We agree that their results support the concept of a common factor underlying the different components of the metabolic syndrome.

What, therefore, are the differences between our studies? The one-factor model in our study was based …

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