Insulin Resistance and Hyperinsulinemia Are Related to Plasma Aldosterone Levels in Hypertensive Patients

Response to Colussi et al.

  1. Antonio Perciaccante, MD,
  2. Alessandra Fiorentini, MD,
  3. Rosita Valente,
  4. Angelo Di Stefano, MD and
  5. Luigi Tubani, MD
  1. From the Department of Clinical Medicine, University “La Sapienza,” Rome, Italy
  1. Address correspondence to Antonio Perciaccante, Department of Clinical Medicine, University “La Sapienza,” Viale del Policlinico, 38 00185 Rome, Italy. E-mail: antonioperciaccante{at}libero.it

We read with interest the article by Colussi et al. (1) on the relationship between insulin resistance, hyperinsulinemia, and aldosterone levels in hypertensive patients. The authors observed that the homeostasis model assessment index is correlated with plasma aldosterone. They conclude that in patients with hypertension, this relationship …

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