Monounsaturated Fat–Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects

Response to Paniagua et al.

  1. Karen Z. Walker, PHD and
  2. Kerin O’Dea, PHD
  1. Preventative Cardiology Unit, Baker Heart Research Institute, Melbourne, Australia
  1. Address correspondence to Dr. Karen Z. Walker, Preventative Cardiology Unit, Baker Heart Research Institute, P.O. Box 6492, St. Kilda Road Central, Victoria 8008, Australia. E-mail: karen.walker{at}baker.edu.au

We were interested in the demonstration by Paniagua et al. (1) that in obese insulin-resistant individuals, high-carbohydrate diets but not high-fat diets (either high monounsaturated [MUFA] or high saturated [SFA]) are associated with some redistribution of fat mass to abdominal rather than peripheral deposits. Their study confirms our earlier findings with high-carbohydrate and high-MUFA diets in people with type 2 diabetes …

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