Monounsaturated Fat–Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects
Response to Walker and O’Dea
- Juan Antonio Paniagua, MD, PHD1 and
- Antonio Vidal-Puig, MD, PHD2
- 1Ciber Fisiopatología Obesidad y Nutrición (CB06/03), Instituto Salud Carlos III, Córdoba, Spain
- 2Molecular Mechanisms of Energy Balance, University of Cambridge, Cambridge, U.K
- Address correspondence to Juan A. Paniagua Gonzalez, Unidad de Lípidos y Arteriosclerosis, Hospital Universitario Reina Sofía, Avda Menéndez Pidal, s/n. 14004, Córdoba, Spain. E-mail: japaniaguag{at}yahoo.es
We thank Walker and O’Dea (1) for their interest in our study, wherein we have shown that when centrally overweight insulin-resistant subjects (offspring of obese and type 2 diabetic patients) are subjected to a short-term, weight-maintenance, carbohydrate-enriched diet, they redistribute their fat mass toward the abdominal fat depot (2). Walker and O’Dea (1) raised the concern that in our study, no significant differences in body weight and body fat distribution were observed when subjects were fed isocaloric diets enriched either with monounsaturated (MUFA) …
