High Titer of Autoantibodies to GAD Identifies a Specific Phenotype of Adult-Onset Autoimmune Diabetes
Response to Kobayashi et al.
- Raffaella Buzzetti, MD1,
- Antonio Petrone, PHD1,
- Marco Capizzi, MD1,
- Emanuele Bosi, MD2 and
- for the Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study Group
- 1Department of Clinical Sciences, “La Sapienza” University, Rome, Italy
- 2Department of General Medicine, Diabetes and Endocrinology, San Raffaele Vita-Salute University, Milan, Italy
- Address correspondence to Raffaella Buzzetti, MD, Department of Clinical Sciences, “La Sapienza” University, Rome, Italy. E-mail: raffaella.buzzetti{at}uniroma1.it
In our article (1) on adult-onset autoimmune diabetes, titers of antibodies to GAD (GADA) are reported in arbitrary units, i.e., they are elaborated in-house; therefore, they are unsuitable for comparison with other studies. However, as anticipated by Kobayashi et al. (2), the participation in the Diabetes Antibody Standardization Program (3) allows us to convert these measurements into World Health Organization (WHO) units. The value of 32 units, which in our study …
