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Effects of Maternal Diabetes on Visual Evoked Potentials and Early Psychomotor Development of the Offspring

  1. Mario Brinciotti, MD1,
  2. Maria Matricardi, MD, PHD1,
  3. Antonietta Colatrella, MD2,
  4. Francesco Torcia, MD3,
  5. Francesco Fallucca, MD2 and
  6. Angela Napoli, MD2
  1. 1Department of Child Neuropsychiatry and Rehabilitation Sciences, Faculty of Medicine I, “Sapienza” Rome University, Rome, Italy
  2. 2Department of Clinical Sciences, Diabetes Unit, Faculty of Medicine II, “Sapienza” Rome University, Rome, Italy
  3. 3Department of Gynecology, Perinatology, and Child Health, Faculty of Medicine II, “Sapienza” Rome University, Rome, Italy
  1. Address correspondence to Mario Brinciotti, MD, Child Neuropsychiatry and Rehabilitation Sciences, “Sapienza” Rome University, Via dei Sabelli, 108, 00185 Rome, Italy. E-mail: mario.brinciotti{at}uniroma1.it

Planning and intensive treatment of diabetes in pregnancy has resulted in dramatic improvements in outcomes in terms of congenital malformations or perinatal morbidity (1), but it is still not clear to what extent maternal diabetes affects cognitive development of newborns. In infants of diabetic mothers (IDMs), significant relations have been reported between poor maternal metabolic regulation during pregnancy and poor child intellectual performance, despite an achievement of overall healthy neuropsychological functioning …

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