Vitamin D, Parathyroid Hormone Levels, and the Prevalence of Metabolic Syndrome in Community-Dwelling Older Adults
Response to Reis et al.
- Giuseppe Lippi, MD1,
- Martina Montagnana, MD1,
- Giovanni Targher, MD2 and
- Gian Cesare Guidi, MD1
- 1Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università di Verona, Italy
- 2Sezione di Endocrinologia e Malattie del Metabolismo, Dipartimento di Scienze Biomediche e Chirurgiche, Università di Verona, Italy
- Address correspondence to Prof. Giuseppe Lippi, MD, Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37134 Verona, Italy. E-mail: ulippi{at}tin.it
We read with interest the recent article by Reis et al. (1), who concluded that neither parathyroid hormone (PTH) nor 25-hydroxyvitamin-D [25(OH)D] level predicts any of the three biochemical components (hyperglycemia, hypertriglyceridemia, and low HDL cholesterol) of metabolic syndrome. Since 25(OH)D and PTH may play a role in the etiology of metabolic syndrome, we retrospectively analyzed associations between results of PTH, 25(OH)D, fasting plasma glucose (FPG), triglycerides, and HDL cholesterol tests, which were performed on an entire cohort of outpatients aged >35 years who were consecutively referred to our clinical laboratory by general practitioners for routine blood testing over the past 2 years.
Venous blood …
