Effect of Periodontitis on Overt Nephropathy and End-Stage Renal Disease in Type 2 Diabetes
Response to Varon
- Wendy A. Shultis, PHD12,
- E. Jennifer Weil, MD1,
- Helen C. Looker, MBBS13,
- Jeffrey M. Curtis, MD, MPH1,
- Marc Shlossman, DDS, MS45,
- Robert J. Genco, DDS, PHD4,
- William C. Knowler, MD, DRPH1 and
- Robert G. Nelson, MD, PHD1
- 1Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona
- 2Center for Public Health Nutrition, University of Washington, Seattle, Washington
- 3Mount Sinai School of Medicine, New York, New York
- 4Department of Oral Biology, State University of New York at Buffalo, Buffalo, New York, and Phoenix, Arizona
- 5Arizona School of Dentistry and Oral Health, Mesa, Arizona
- Address correspondence to Dr. Robert G. Nelson, National Institutes of Health, 1550 East Indian School Rd., Phoenix, AZ 85014-4972. E-mail: rnelson{at}phx.niddk.nih.gov
We thank Dr. Varon (1) for his interest in the relationship between periodontitis and kidney disease in type 2 diabetes, but we disagree with most of his statements and conclusions.
First, although our analysis (2) excluded individuals with kidney disease (macroalbuminuria or low glomerular filtration rate) at baseline, we did not exclude individuals with known risk factors for …
