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Consensus Statement on the Worldwide Standardization of the Hemoglobin A1C Measurement: the American Diabetes Association, European Association for the Study of Diabetes, International Federation of Clinical Chemistry and Laboratory Medicine, and the International Diabetes Federation

Response to the Consensus Committee

  1. George Treviño, PHD
  1. From CHIRES, Inc., San Antonio, Texas
  1. Address correspondence to George Treviño, PhD, CHIRES, Inc., P.O. Box 201481, San Antonio, TX 78220. E-mail: trevinochires{at}mac.com

I read with keen interest the statement of the Consensus Committee on the pending worldwide standardization of hemoglobin A1C measurement (1) and felt compelled to offer a more “believable” reason why the data supporting the premise that A1C assay reflects average glycemia over the preceding few months “are not exceptionally robust.” The Consensus Committee contends that “glucose concentrations were not measured frequently enough to compute a true ‘average.'”

The more believable reason is this: a variation of parameter analysis was carried out in ref. 2, and it was …

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