Randomized Trial of Behavioral Family Systems Therapy for Diabetes
Maintenance of effects on diabetes outcomes in adolescents
- Tim Wysocki, PHD1,
- Michael A. Harris, PHD2,
- Lisa M. Buckloh, PHD1,
- Debbie Mertlich, LCSW2,
- Amanda S. Lochrie, PHD1,
- Nelly Mauras, MD1 and
- Neil H. White, MD, CDE23
- 1Department of Biomedical Research, Nemours Children’s Clinic, Jacksonville, Florida
- 2Washington University in St. Louis School of Medicine, St. Louis, Missouri
- 3St. Louis Children’s Hospital, St. Louis, Missouri
- Address correspondence and reprint requests to Tim Wysocki, PhD, Nemours Childrens Clinic, Department of Biomedical Research, 807 Children’s Way, Jacksonville, FL 32207. E-mail: twysocki{at}nemours.org
Abstract
OBJECTIVE—Studies showing that family communication and conflict resolution are critical to effective management of type 1 diabetes in adolescents have stimulated interest in evaluating psychological treatments targeting these processes. Previous trials have shown that Behavioral Family Systems Therapy (BFST) improved parent-adolescent relationships but not treatment adherence or glycemic control. This study evaluates a revised intervention, BFST for Diabetes (BFST-D), modified to achieve greater impact on diabetes-related family conflict, treatment adherence, and metabolic control.
RESEARCH DESIGN AND METHODS—A sample of 104 families of adolescents with inadequate control of type 1 diabetes was randomized to either remain in standard care (SC) or to augmentation of that regimen by 12 sessions of either a multifamily educational support (ES) group or 12 sessions of BFST-D over 6 months. Pertinent measures were collected at baseline and at follow-up evaluations at 6, 12, and 18 months.
RESULTS—BFST-D was significantly superior to both SC and ES in effects on A1C, while effects on treatment adherence and family conflict were equivocal. Improvement in A1C appeared to be mediated by improvement in treatment adherence. A significantly higher percentage of BFST-D youth achieved moderate or greater improvement (>0.5 SD) in treatment adherence compared with the SC group at each follow-up and the ES group at 6 and 18 months. Change in treatment adherence correlated significantly with change in A1C at each follow-up.
CONCLUSIONS—These results support the efficacy of BFST-D in improving A1C, but further research is needed to identify the mechanisms of this effect and to achieve cost-effective dissemination of the intervention.
- BFST, Behavioral Family Systems Therapy
- BFST-D, Behavioral Family Systems Therapy for Diabetes
- DRC, Diabetes Responsibility and Conflict
- DSMP, Diabetes Self-Management Profile
- ES, educational support
- SC, standard care
Footnotes
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A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.
The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C Section 1734 solely to indicate this fact.
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- Accepted November 28, 2006.
- Received July 31, 2006.
- DIABETES CARE














