Plasma Retinol-Binding Protein-4 Concentrations Are Elevated in Human Subjects With Impaired Glucose Tolerance and Type 2 Diabetes
Response to Gavi et al.
- Young Min Cho, MD, PHD12,
- Byung-Soo Youn, PHD34 and
- Kyong Soo Park, MD, PHD12
- 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- 2Genome Research Center for Diabetes and Endocrine Disease, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
- 3AdipoGen, Inc., College of Life Science and Biotechnology, Korea University, Seoul, Korea
- 4Immunomodulation Research Center, University of Ulsan, Ulsan, Korea
- Address correspondence to Kyong Soo Park, MD, PhD, Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, Korea. E-mail: kspark{at}snu.ac.kr
Gavi et al. (1) investigated the association between visceral adipose tissue (VAT) mass by computed tomography and circulating retinol-binding protein-4 (RBP4) concentrations in nondiabetic subjects. They could not find a correlation between VAT and serum RBP4 concentrations, while VAT was inversely correlated with serum adiponectin concentrations in their subjects. The study by Gavi et al. did not support specific association between circulating …
