The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes

  1. Justin A. Altschuler, BA1,
  2. Samuel J. Casella, MD2,
  3. Todd A. MacKenzie, PHD3 and
  4. Kevin M. Curtis, MD4
  1. 1Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire
  2. 2Department of Pediatric Endocrinology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
  3. 3Department of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
  4. 4Department of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
  1. Address correspondence and reprint requests to Kevin M. Curtis, MD, Assistant Professor of Medicine, Dartmouth-Hitchcock Medical Center, Section of Emergency Medicine, 1 Medical Center Dr., Lebanon, NH 03756. E-mail: kevin.m.curtis{at}hitchcock.org

Abstract

OBJECTIVE—The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type 1 diabetes.

RESEARCH DESIGN AND METHODS—Using a prospective, double-blind, placebo-controlled design, 72 adolescent type 1 diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. A1C, total daily insulin intake, and adverse events were recorded and compared between groups.

RESULTS—There were no significant differences in final A1C (8.8 vs. 8.7, P = 0.88), change in A1C (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms.

CONCLUSIONS—Cinnamon is not effective for improving glycemic control in adolescents with type 1 diabetes.

Footnotes

  • Clinical trial reg. no. NCT00365170, clinicaltrials.gov.

    A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

    The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C Section 1734 solely to indicate this fact.

    • Accepted December 31, 2006.
    • Received September 7, 2006.
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