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Clinical Implications of the DREAM Study

Response to Davidson

  1. Mustafa Kanat, MD
  1. From the Department of Internal Medicine, Bolu Izzet Baysal Medical School, Abant Izzet Baysal University, Bolu, Turkey
  1. Address correspondence to Mustafa Kanat, Abant Izzet Baysal University, Bolu Izzet Baysal Medical School, Department of Internal Medicine, 14280-Golkoy, Bolu, Turkey

The following points should be taken into consideration when determining “what circumstances TZDs [thiazolidinediones] should be used in people without documented diabetes,” as questioned by the commentary published in the February issue of Diabetes Care (1).

The DREAM (Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication) study (2) has limitations that prevent generalizations for individuals with impaired fasting …

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