IGF-Binding Protein-1 Levels Are Related to Insulin-Mediated Glucose Disposal and Are a Potential Serum Marker of Insulin Resistance
Response to van Haeften et al.
- Betty A. Maddux, BS1,
- Adeline Chan, BS1,
- Elena A. De Filippis, MD2,
- Lawrence J. Mandarino, PHD2 and
- Ira D. Goldfine, MD1
- 1Diabetes Center, Department of Medicine, University of California, San Francisco, California
- 2School of Life Science, Arizona State University, Tempe, Arizona
- Address correspondence to Dr. Ira Goldfine, UCSF, 2200 Post, C415, San Francisco, CA 94143-1616. E-mail: ira.goldfine{at}ucsf.edu
We appreciate the interest of van Haeflen et al. (1) in our article (2) concerning IGF-binding protein (IGFBP)-1 as a maker of insulin resistance in healthy nondiabetic subjects. In contrast to our study, they did not find a strong a correlation between insulin action as determined …
