Recruiting High-Risk Individuals to a Diabetes Prevention Program

How hard can it be?

  1. Toralph Ruge, MD, PHD1,
  2. Lennarth Nyström, PHD2,
  3. Bernt Lindahl, MD, PHD2,
  4. Göran Hallmans, MD, PHD2,
  5. Margareta Norberg, MD2,
  6. Lars Weinehall, MD, PHD2 and
  7. Olov Rolandsson, MD, PHD2
  1. 1Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden
  2. 2Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
  1. Address correspondence to Olov Rolandsson, MD, PhD, Family Medicine, Department of Public Health and Clinical Medicine, X3, SE-901 85, Umeå University, Umeå, Sweden. E-mail: olov.rolandsson{at}

Lifestyle prevention programs in Finland (Diabetes Prevention Study [DPS]) (1,2) and the U.S. (Diabetes Prevention Program [DPP]) (3) have shown that the development of type 2 diabetes can be prevented. A cost-effectiveness study revealed that lifestyle intervention was effective in all ages (4). Whether lifestyle intervention will be cost-effective in the general population is determined by 1) the recruitment of the majority of high-risk individuals and 2) the compliance to lifestyle changes.

We studied the recruitment rate in an open, randomized, and controlled trial aiming to reduce the incidence of diabetes. Intervention consisted of physical activity and dietary information that was to be organized by a nonprofit organization for the intervention …

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