What Dose of Folic Acid Should Be Used for Pregnant Diabetic Women?
- Ismael Capel, MD1 and
- Rosa Corcoy, MD, PHD12
- 1Department of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
- 2CIBER Bioengineering, Biomaterials and Nanotechnology, Instituto de Salud Carlos III, Madrid, Spain
- Address correspondence to Ismael Capel, Department of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Sant Antoni M. Claret, 167-08025, Barcelona, Spain. E-mail: icapelf{at}santpau.es
It is well established that folate requirements increase during pregnancy and that supplementing 0.4 mg folic acid/day to the general pregnant population is beneficial in terms of reducing the risk of neural tube defects (NTDs). Offspring of women with pregestational diabetes mellitus have an increased risk of congenital anomalies, including NTDs (1). In animal models, …
