Effect of Chromium Supplementation on Glucose Metabolism and Lipids: A Systematic Review of Randomized Controlled Trials
Response to Balk et al.
- Nanne Kleefstra, MD12,
- Sebastiaan T. Houweling, MD, PHD2 and
- Henk J.G. Bilo, MD, PHD, FRCP1
- 1Diabetes Centre, Isala Clinics, Zwolle, the Netherlands
- 2Langerhans Medical Research Group, Langerhans Foundation, Zwolle, the Netherlands
- Address correspondence to Nanne Kleefstra, MD, Langerhans Foundation, Diabetes Centre, Isala Clinics, Sophia Location, P.O. Box 10400, 8000 GK Zwolle, Netherlands. E-mail: kleefstra{at}langerhans.com
With interest, we read the systematic review by Balk et al. (1). It reviewed the effect of chromium supplementation on glucose metabolism and lipids. It is important to have an update of the systematic review performed by Althuis et al. (2) in 2002, since many studies have been published in the years thereafter.
However, we have some concerns with the conclusions of the current systematic review (1). Althuis et al. (2 …











