Weight Gain and Gestational Diabetes Mellitus Is a Sensitive Issue
- Wendy C. Bevier, PHD and
- Lois Jovanovič, MD
- From the Sansum Diabetes Research Institute, Santa Barbara, California
- Address correspondence to Lois Jovanovič, MD, Sansum Diabetes Research Institute, 2219 Bath St., Santa Barbara, CA 93105. E-mail: ljovanovic{at}sansum.org
Normal pregnancy is associated with reduced insulin sensitivity, compensatory increase in insulin secretion, and small changes in circulating nutrients. Gestational diabetes mellitus (GDM) occurs when insulin secretion is insufficient to compensate for the insulin resistance of pregnancy. During late pregnancy, women with GDM tend to be more insulin resistant than obesity-matched women with normal glucose tolerance (1). Little is known about the effects of weight gain in the third trimester versus no weight gain or weight loss as treatments for GDM. The objective of our study was to determine the effect of medical nutrition therapy (MNT) on insulin sensitivity (S …
