Primary Aldosteronism in Diabetic Subjects With Resistant Hypertension

Response to Umpierrez et al.

  1. Ying Wai Ng, MBCHB,
  2. Sau Cheung Tiu, MD,
  3. Jason Chiu Ming Ng, MBCHB and
  4. Hiu Yan Chan, MBCHB
  1. From the Department of Medicine, Queen Elizabeth Hospital, Hong Kong, China
  1. Address correspondence to Dr. Ying Ng, Queen Elizabeth Hospital, Medicine, 30 Gascoigne Rd., Kowloon, Hong Kong, China. E-mail: ngyingwai{at}hotmail.com

We read with interest the article by Umpierrez et al. in a recent issue of Diabetes Care (1). Primary aldosteronism, a condition associated with suppressed renin and angiotensin levels, is known to be associated with a higher incidence of cardiovascular complications and increased mortality compared with that in patients with comparable blood pressure levels due to essential hypertension. On the other hand, activation of the renin-angiotensin system, manifesting as …

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