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Primary Aldosteronism in Diabetic Subjects With Resistant Hypertension

Response to Ng et al.

  1. Dawn Smiley, MD and
  2. Guillermo Umpierrez, MD
  1. From the Endocrinology Section, Emory University, Atlanta, Georgia
  1. Address correspondence to Guillermo E. Umpierrez, MD, Endocrinology Section, Emory University, 49 Jesse Hill Jr. Dr., Atlanta, Georgia

We reported that hypertension affects nearly 70% of patients with type 2 diabetes at our institution and that 45% of them require three or more antihypertensive agents (1). Despite the multidrug approach, one-third of patients do not achieve the recommended blood pressure goal of <130/80 mmHg. These findings led us to investigate the prevalence of primary hyperaldosteronism (PHA), the most common cause of endocrine hypertension, in diabetic patients with resistant hypertension. We found that 14% of diabetic patients with resistant hypertension had biochemical evidence of PHA. Thus, select patients with diabetes should …

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