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Comparison of Negative Pressure Wound Therapy Using Vacuum-Assisted Closure With Advanced Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers: a Multicenter Randomized Controlled Trial

Response to Hemkens and Waltering

  1. Peter A Blume, DPM
  1. From the North American Center for Limb Preservation, New Haven, Connecticut
  1. Corresponding author: Peter A. Blume, peter.b{at}snet.net

We appreciate Dr. Hemkens and Dr. Waltering's (1) comments on our recently published article on the use of negative pressure wound therapy (NPWT) as delivered by vacuum-assisted closure therapy in the treatment of diabetic foot ulcers (2).

We thank Hemkens and Waltering for recognizing the difficulty in conducting this randomized clinical trial in a blinded fashion. However, we did insure that therapy selection was conducted in a blinded fashion. Neither the physician nor the patient was aware of the treatment assignment before enrolling. Hemkins and Waltering also state that there was a high proportion of censored subject data (33%, n = 11). Given age, health …

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