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Determinants for the Effectiveness of Lifestyle Intervention in the Finnish Diabetes Prevention Study

Response to Schulze

  1. Jaana Lindström, PHD12,
  2. Markku Peltonen, PHD1 and
  3. Jaakko Tuomilehto, MD, MPH, PHD12
  1. 1Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
  2. 2Department of Public Health, University of Helsinki, Helsinki, Finland
  1. Corresponding author: Jaana Lindström, jaana.lindstrom{at}ktl.fi

In our recent publication (1), we showed that among participants in the Finnish Diabetes Prevention Study, a diabetes prevention trial using lifestyle intervention, those who had the highest baseline composite diabetes risk as measured by the Finnish Diabetes Risk Score (FINDRISC) achieved the largest risk reduction during the lifestyle intervention.

We appreciate the comment written by Schulze. However, the major part of the comment addresses our earlier publication (3) describing the development and validation of the risk prediction model using two large, population-based cohorts. In that paper, we extensively discussed the issues raised by …

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