Association of 1,5-Anhydroglucitol and 2-h Postprandial Blood Glucose in Type 2 Diabetic Patients

Response to Stettler et al.

  1. Roger K. Schindhelm, MD, PHD, MEPI1,
  2. Michaela Diamant, MD, PHD2,
  3. Henk J. Bilo, MD, PHD, FRCP3 and
  4. Robbert J. Slingerland, PHD1
  1. 1Department of Clinical Chemistry, Isala Clinics, Zwolle, the Netherlands
  2. 2Department of Endocrinology/Diabetes Center, VU University Medical Center, Amsterdam, the Netherlands
  3. 3Department of Internal Medicine/Diabetes Center, Isala Clinics, Zwolle, the Netherlands
  1. Corresponding author: Roger K. Schindhelm, r.k.schindhelm{at}isala.net

In their very elegant study, Stettler et al. (1) assessed the association between 1,5-anhydroglucitol (1,5-AG) and postprandial glucose during different time periods, varying from 3 days to 12 weeks long, in patients with type 2 diabetes. They found the strongest association during a 2-week period. Although the authors excluded patients with overt renal insufficiency or proteinuria, it is as yet unknown whether additional adjustments for …

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