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“Abnormal” Fasting Plasma Glucose During Pregnancy

  1. Veerasamy Seshiah, MD,
  2. Vijayam Balaji, MD,
  3. Arunachalam Panneerselvam, MD and
  4. Madhuri S. Balaji, MB
  1. From the Diabetes In Pregnancy—Awareness and Prevention (DIPAP) Project, Dr V Seshiah Diabetes Care and Research Institute, Chennai, Tamil Nadu, India
  1. Corresponding author: Veerasamy Seshiah, vseshiah{at}gmail.com

Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy (1) and is a major medical complication of pregnancy. Untreated, the would-be mother and yet-to-be-born child are likely to suffer morbidity and mortality.

The World Health Organization criterion for diagnosis of GDM is 2-h plasma glucose (PG) ≥140 mg/dl on a 75-g oral glucose tolerance test (2). However, birth weight of the child and cumulative risk of type 2 diabetes both increase with any rise in 2-h PG ≥120 mg/dl (3). Further, data regarding the correlation between maternal fasting PG (FPG) levels and macrosomia are scant. Hence, we analyzed the relationship between the birth weight of neonates …

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